Wednesday, 11 April 2018

Sildenafil and Impurities by Pharmaffiliates


Pharmaffiliates Analytics and Synthetics Pvt. Ltd, a substantial and predominant name as manufacturer and supplier of impurity standards globally, proudly introduces a wide range of premium quality products at highly competitive prices.
Sildenafil is an eminent first-line therapy for erectile dysfunction and works by selectively inhibiting phosphodiesterase type 5, which allows corpus cavernosum smooth muscle to relax, potentiating erections during sexual stimulation. 
Pharmaffiliates offers a vast variety of Sildenafil impurity standards which includes both commercially available and unavailable standards. All the standards are provided in the pack size of 25mg of 50mg and these packs can be customized as per customer's requirement also.
Each standard is shipped with a Certificate of Analysis, MSDS, and all the required documentation to ensure statutory domestic and international reputations. Our standards are of high purity and are scientifically characterized.
Our laboratory and quality systems have successfully passed major second and third party audits which include NABL accreditation, ISO Guide 34 and USFDA.
Pharmaffiliates offers below listed impurity standards of Sildenafil:
Name of the impurity
Product Code
CAS No.
Application
PA 19 09010
1391053-95-4
An impurity (Isobutyl Sildenafil

Sildenafil - impurity B

PA 19 09020
1094598-75-0
A prodrug (Sildenafil N-oxide)

Sildenafil - impurity C


PA 19 09030
139755-91-2
A metabolite (Desethyl Sildenafil)
PA 19 09040
1357931-55-5
An impurity (Demethylpiperazinyl Sildenafil Sulfonic Acid)
PA 19 09050
288-32-4
By-product (Imidazole)
PA 19 09070
1346602-67-2
Dimer impurity

Sildenafil aldehyde

PA 19 09510
332374-42-2
Intermediate in synthesis

Sildenafil amino amide impurity 

PA 19 09520 (Freebase)/ PA 19 09530 (Hydrochloride salt)
139756-02-8/ 247584-10-7
Intermediate in synthesis

Sildenafil chloro impurity 

PA 19 09540
Important reactant for Sildenafil synthesis

Sildenafil carboxamide impurity 

PA 19 09550
An impurity

Sildenafil lactam impurity

PA 19 09560
An impurity

Sildenafil chlorosulfonyl impurity 

PA 19 09570
An impurity

N-Desmethyl Sildenafil

PA 19 09580
An active metabolite

4-Ethoxy-N,N-bis(2-hydroxyethyl)-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1h-pyrazolo[4,3-d]pyrimidin-5-yl)benzenesulfonamide

PA 19 09590
NA
An impurity

O-Desethyl-o-propyl methisosildenafil

PA 19 09600
An analog

Propoxyphenyl homohydroxy Sildenafil 

PA 19 09610
An analog of Homo Sildenafil

Propoxyphenyl Sildenafil

PA 19 09620
An impurity

Descarbon Sildenafil 

PA 19 09630
An analog

5-(5-Carboxy-2-ethoxyphenyl)-1-methyl-3-N-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one 

PA 19 09640
A metabolite of Gendenafil, an analog of Sildenafil

4-Amino-1-methyl-5-propyl-1h-pyrazole-3-carboxamide

PA 19 09650
An intermediate

Sildenafil amide impurity

PA 19 09660
139756-01-7
An impurity

Sildenafil methyl sulfonate ester impurity 

PA 19 09670
NA
An impurity

1-Methyl-4-nitro-3-propyl-1h-pyrazole-5-carboxylic acid

PA 19 09680
An intermediate

Demethylpiperazinyl Iso Sildenafil sulfonyl chloride

PA 19 09690
501120-42-9
An intermediate of Sildenafil and Iso Sildenafil

(Z)-N'-(5-Chloro-4-methyl-2-propyl-1H-imidazol-1-yl)-2-ethoxy-5-((4-ethylpiperazin-1-yl)sulfonyl)benzimidamide

PA 19 09700
NA
An impurity

(Z)-N'-(5-Chloro-4-methyl-2-propyl-1H-imidazol-1-yl)-2-ethoxybenzimidamide 

PA 19 09710
NA
An impurity


You can order the above-mentioned impurity standards here:
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